SCHEMBL282772

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10127056	0.91	GFER (0.47)	GFERRXFP1XDHBUB1TGFBR1
	SCHEMBL10127047	0.89	GFER (0.45)	GFERRXFP1XDHTGFBR1
	SCHEMBL10157179	0.87	GFER (0.43)	GFERRXFP1CSNK2A1XDHNEK2
	SCHEMBL10127123	0.83	CAMK1D (0.46)	GFERRXFP1
	SCHEMBL10126587	0.82	XDH (0.39)	GFERRXFP1XDH
	SCHEMBL10156468	0.82	XDH (0.39)	GFERRXFP1XDHSCN9A
	SCHEMBL10156444	0.82	MAPK14 (0.42)	—
	SCHEMBL10126474	0.82	XDH (0.43)	GFERRXFP1XDH
	SCHEMBL16305333	0.82	TNNI3K (0.49)	EGFR
	SCHEMBL282649	0.82	CSNK2A1 (0.42)	CSNK2A1CSNK2A2CSNK2BBUB1NEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.