Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30004111 | 0.81 | PPARG (0.48) | LCK | |
| SCHEMBL21839363 | 0.81 | PPARG (0.48) | LCK | |
| SCHEMBL21839366 | 0.81 | PPARG (0.48) | LCK | |
| SCHEMBL30003962 | 0.81 | PPARG (0.48) | LCK | |
| SCHEMBL21855311 | 0.81 | PPARG (0.48) | LCK | |
| SCHEMBL30767153 | 0.81 | PPARG (0.48) | LCK | |
| SCHEMBL28277422 | 0.81 | FBP1 (0.45) | KDM4EFBP1PTGS2L3MBTL1 | |
| SCHEMBL1068427 | 0.79 | LMNA (0.49) | KDM4EFBP1NR1I2SMN1; SMN2L3MBTL1 | |
| SCHEMBL18099125 | 0.77 | ESR1 (0.50) | KDM4EPTGS2PTGS1L3MBTL1 | |
| SCHEMBL21855405 | 0.77 | PPARG (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438206-A | A method of the asymmetric single carbonyl curcumin analog intermediate of synthesis | 温州医科大学 | 2019-03-08 | — | — | CN | disclosed |