Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.65 |
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610887 | 0.93 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL9874228 | 0.91 | NPC1 (0.61) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL14223444 | 0.83 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL28143734 | 0.81 | NPC1 (0.68) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12077529 | 0.81 | NPC1 (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4863530 | 0.81 | KDM4E (0.59) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL393417 | 0.80 | ALDH1A1 (0.48) | RAB9ANPC1SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL4861878 | 0.80 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11451378 | 0.80 | SMN1; SMN2 (0.60) | RAB9ANPC1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL4853047 | 0.79 | NPC1 (0.61) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093372-B | Synthesis method of imidazole derivative | 安徽工程大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-115093372-A | Synthesis method of imidazole derivative | 安徽工程大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-113264899-B | 1,3,5-oxadiazine compound and preparation and application thereof | 台州学院 | 2022-06-14 | — | — | CN | disclosed |
| CN-113264899-A | 1,3,5-oxadiazine compound and preparation and application thereof | 台州学院 | 2021-08-17 | — | — | CN | disclosed |
| CN-111533706-B | Preparation method of 1,4, 6-trisubstituted 1, 2-dihydro-triazine compound | 台州学院 | 2021-08-03 | — | — | CN | disclosed |
| CN-111533706-A | Preparation method of 1,4, 6-trisubstituted 1, 2-dihydro-triazine compound | 台州学院 | 2020-08-14 | — | — | CN | disclosed |
| CN-109468659-A | The method of room temperature synthesizing benzimidazole under the conditions of electrocatalytic method water phase | 云南师范大学 | 2019-03-15 | — | — | CN | disclosed |
| CN-109456273-A | The method of benzenecarboximidamide class compound synthesis benzimidazole compound is used in microwave method water phase | 云南师范大学 | 2019-03-12 | — | — | CN | disclosed |