Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28276291 | 0.90 | KAT8 (0.48) | CA2METAP2KAT8PLK1ALDH1A1 | |
| SCHEMBL28277680 | 0.86 | CNR1 (0.42) | CNR1CNR2POLBCTDSP1CA2 | |
| SCHEMBL28277786 | 0.86 | RAB9A (0.49) | CA2MAPTRAB9AMETAP2ALDH1A1 | |
| SCHEMBL28271984 | 0.84 | KAT8 (0.51) | CNR1CNR2POLBCTDSP1MAPT | |
| SCHEMBL8282580 | 0.81 | ESR1 (0.40) | CNR1CNR2POLBCA2MAPT | |
| SCHEMBL27543183 | 0.80 | ERN1 (0.40) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL10211144 | 0.79 | CNR1 (0.42) | CNR1CNR2MAPTRAB9AMETAP2 | |
| SCHEMBL8876740 | 0.77 | PLK1 (0.43) | CNR1CNR2POLBCTDSP1MAPT | |
| SCHEMBL28011859 | 0.77 | BACE1 (0.46) | CNR1CNR2CA2MAPTRAB9A | |
| SCHEMBL23937803 | 0.77 | KDM4E (0.57) | CNR1CNR2MAPTRAB9AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293585-A | A method of halobenzamides rapid synthesis quinazolinones are utilized under microwave condition in water phase | 云南师范大学 | 2019-02-01 | — | — | CN | disclosed |