SCHEMBL28278136

SCHEMBL28278136

CCOC(=O)NN.Nc1nc(N)nc(N)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
GAA P10253 3/20 0.44
KDM4E B2RXH2 4/20 0.44
TSHR P16473 1/20 0.41
GLA P06280 1/20 0.39
POLB P06746 1/20 0.39
CYP1A2 P05177 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
RECQL P46063 1/20 0.39
MAPK1 P28482 1/20 0.38
ALOX15 P16050 1/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170635 0.85
Hydrochloric Acid SCHEMBL10500748 0.83
SCHEMBL8108672 0.83
Alcohol SCHEMBL28651029 0.81 GAA (0.46) ALDH1A1GAAKDM4ECYP1A2ALOX15
Ethylene SCHEMBL27616164 0.81
SCHEMBL27824132 0.78 ALDH1A1 (0.48) ALDH1A1GAAKDM4ETSHRCYP1A2
Sulfuric Acid SCHEMBL11065873 0.77 GAA (0.42) ALDH1A1GAAKDM4ECYP1A2HPGD
SCHEMBL27818416 0.77 GAA (0.42) ALDH1A1GAAKDM4ETSHRGLA
Urethane SCHEMBL5693672 0.77 ALOX15 (0.68) ALDH1A1GAAKDM4ETSHRCYP1A2
Ethyl Acetate SCHEMBL27589856 0.77 ALDH1A1 (0.64) ALDH1A1GAAKDM4ETSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311810-A Use of compounds for the preparation of products having at least one N-halamine precursor group and at least one cationic center 埃克斯根杰技术公司 2019-02-05 CN disclosed