⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56200 | 0.81 | — | — | |
| SCHEMBL317315 | 0.80 | — | — | |
| SCHEMBL727185 | 0.79 | CYP1A2 (0.62) | — | |
| SCHEMBL724866 | 0.79 | CHRNA7 (0.74) | — | |
| SCHEMBL29485692 | 0.79 | CHRNA7 (0.74) | — | |
| SCHEMBL2093515 | 0.78 | CYP2A6 (0.66) | — | |
| Ethylene SCHEMBL11852796 | 0.76 | CYP1A2 (0.54) | — | |
| Nicotinyl Alcohol SCHEMBL2476584 | 0.76 | KDM4E (0.65) | — | |
| SCHEMBL2095573 | 0.76 | TDP1 (0.67) | — | |
| SCHEMBL7214218 | 0.76 | CYP1A2 (0.77) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2468 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3513792-B9 | MORPHINAN DERIVATIVES FOR THE TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASES | NIPPON CHEMIPHAR CO (JP) | 2024-07-10 | — | — | EP | claimed |
| CN-118055773-A | Lipopeptides inhibitors of interleukin-23 receptor | 詹森生物科技公司 | 2024-05-17 | — | — | CN | claimed |
| US-20240156796-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF STRESS-RELATED DISORDERS | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2024-05-16 | — | — | US | claimed |
| CN-114853729-B | Quinazoline-2-ketone compound and preparation method and application thereof | 汕头大学医学院 | 2024-03-29 | — | — | CN | claimed |
| EP-3513792-B1 | MORPHINAN DERIVATIVES FOR THE TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASES | NIPPON CHEMIPHAR CO (JP) | 2024-03-27 | — | — | EP | claimed |
| EP-4299074-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF STRESS-RELATED DISORDERS | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2024-01-03 | — | — | EP | claimed |
| WO-2023222644-A1 | PYRAZOLE DERIVATIVES AS STING AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-11-23 | — | — | WO | claimed |
| CN-116997360-A | Pharmaceutical composition for treating or preventing stress-related disorders | 学校法人东京理科大学 | 2023-11-03 | — | — | CN | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| WO-2023023513-A9 | STABILIZATION OF OLIGONUCLEOTIDE AND OLIGONUCLEOTIDE-PROTEIN COMPLEX USING ALKYLATED PHOSPHATE | UNIVERSITY OF MASSACHUSETTS (US) | 2023-06-01 | — | — | WO | claimed |
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | claimed |
| US-5256668-A | Aminopyrimidine derivatives as antiviral agents for respiratory syncytial virus | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-26 | — | — | US | claimed |
| EP-0565631-A1 | ANTI-VIRAL COMPOUNDS. | MERRELL DOW PHARMA (US) | 1993-10-20 | — | — | EP | claimed |
| WO-1992019593-A1 | NOVEL IMMUNOSUPPRESSIVE COMPOUNDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1992-11-12 | — | — | WO | claimed |
| CN-1064269-A | The 4-Pyrimdinone derivatives, their preparation method and they application in treatment | SYNTHELABO (FR) | 1992-09-09 | — | — | CN | claimed |
| WO-1992012123-A1 | ANTI-VIRAL COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-23 | — | — | WO | claimed |
| EP-0300865-B1 | DERIVATIVES OF N-AMINOBUTYL-N-PHENYL ARYL AMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SYNTHELABO (FR) | 1992-03-18 | — | — | EP | claimed |
| US-5091425-A | Inhibitors of the catalytic action of renin | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | claimed |
| US-5075325-A | Cardiovascular disorders | SYNTHELABO (FR) | 1991-12-24 | — | — | US | claimed |
| EP-0369743-A2 | Heterocyclic amides | ZENECA LIMITED (GB) | 1990-05-23 | — | — | EP | claimed |