Sugi Predict

Sugi Predict / Compounds / SCHEMBL727185

SCHEMBL727185

SCHEMBL727185

c1cncc(Cc2cccnc2)c1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.62
▸ CYP2D6 P10635 1/20 0.62
▸ HRH4 Q9H3N8 1/20 0.61
▸ HRH3 Q9Y5N1 1/20 0.61
▸ CHRNA7 P36544 2/20 0.60
▸ CYP11B1 P15538 1/20 0.60
▸ CYP11B2 P19099 1/20 0.60
▸ TBXAS1 P24557 3/20 0.58
▸ CHRNB2 P17787 3/20 0.58
▸ CHRNA4 P43681 3/20 0.58
▸ MMP2 P08253 1/20 0.57
▸ CYP2A6 P11509 1/20 0.56
▸ NAPRT Q6XQN6 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177863 0.93 CYP11B1 (0.65) CYP1A2CYP2D6HRH4HRH3CHRNA7
SCHEMBL14257669 0.93 CYP1A2 (0.56) CYP1A2CYP2D6HRH4HRH3CHRNA7
SCHEMBL29995759 0.93 CYP11B1 (0.65) CYP1A2CYP2D6HRH4HRH3CHRNA7
Hydrochloric Acid SCHEMBL10665044 0.91 TBXAS1 (0.64) CYP1A2CYP2D6HRH4HRH3CYP11B1
Ammonia Solution, Strong SCHEMBL5999508 0.91 CYP11B1 (0.62) CYP1A2CYP2D6HRH4HRH3CHRNA7
SCHEMBL24769738 0.91 CYP1A2 (0.54) CYP1A2CYP2D6HRH4HRH3CHRNA7
SCHEMBL16996646 0.85 MMP2 (0.65) CYP1A2CYP2D6HRH4HRH3CHRNA7
SCHEMBL6649631 0.85 TBXAS1 (0.56) CYP1A2CYP2D6HRH4HRH3CYP11B1
SCHEMBL4248371 0.85 TBXAS1 (0.60) CYP11B1CYP11B2TBXAS1
SCHEMBL8081819 0.85 ALDH1A1 (0.66) CYP11B1CYP11B2TBXAS1CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697884-B2 Copper deposition in wafer level packaging of integrated circuits MACDERMID ENTHONE INC. (US) 2023-07-11 — — US disclosed
US-11697884-B2 Copper deposition in wafer level packaging of integrated circuits MACDERMID ENTHONE INC. (US) 2023-07-11 — — US disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 — — US disclosed
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2023-05-18 — — US disclosed
US-20220143201-A1 COMPOSITION COMPRISING A POLYMERIC REAGENT NEKTAR THERAPEUTICS (US) 2022-05-12 — — US disclosed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 — — US disclosed
CN-114420633-A Copper deposition in wafer level packaging of integrated circuits 麦克德米德乐思公司 2022-04-29 — — CN disclosed
CN-109996785-B Copper deposition in wafer level packaging of integrated circuits 麦克德米德乐思公司 2021-12-28 — — CN disclosed
US-20210388519-A1 Copper Deposition in Wafer Level Packaging of Integrated Circuits MACDERMID ENTHONE INC. 2021-12-16 — — US disclosed
US-11124888-B2 Copper deposition in wafer level packaging of integrated circuits MACDERMID ENTHONE INC. (US) 2021-09-21 — — US disclosed
EP-1781635-A2 POTASSIUM CHANNEL INHIBITORS Merck & Co., Inc. (US) 2007-05-09 — — EP disclosed
WO-2007050348-A2 POTASSIUM CHANNEL INHIBITORS MERCK & CO., INC. (US) 2007-05-03 — — WO disclosed
WO-2007050347-A1 POTASSIUM CHANNEL INHIBITORS MERCK & CO., INC. (US) 2007-05-03 — — WO disclosed
EP-1776355-A2 POTASSIUM CHANNEL INHIBITORS Merck & Co., Inc. (US) 2007-04-25 — — EP disclosed
WO-2006028590-A1 1,1,2,2-TETRA (HETERO) ARYLETHANES OR 1,1,2-TRI (HETERO) ARYL-2-HETEROCYCLYLETHANES AS POTASSIUM CHANNEL INHIBITORS MERCK & CO., INC. (US) 2006-03-16 — — WO disclosed
WO-2006015159-A2 POTASSIUM CHANNEL INHIBITORS MERCK & CO., INC. (US) 2006-02-09 — — WO disclosed
US-20060030595-A1 (R)-N-{6-[1-(4-fluorophenyl)-2,2-dipyridin-3-ylethyl]pyridin-2-yl}methanesulfonamide; cardiac arrhythmias MERCK SHARP & DOHME LLC 2006-02-09 — — US disclosed
WO-2006014877-A2 POTASSIUM CHANNEL INHIBITORS MERCK & CO., INC. (US) 2006-02-09 — — WO disclosed
US-5622953-A DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG BASF AKTIENGESELLSCHAFT (DE) 1997-04-22 — — US disclosed
WO-1994022842-A1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1994-10-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143201-A1 COMPOSITION COMPRISING A POLYMERIC REAGENT CD44, FCGRT, C9 CYP1A2 2585/4885CYP2D6 2093/4885HRH4 320/4885
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes FDFT1, SUN2, CDC73 CYP1A2 2358/4885CYP2D6 3070/4885HRH4 2783/4885
US-20060030595-A1 (R)-N-{6-[1-(4-fluorophenyl)-2,2-dipyridin-3-ylethyl]pyridin-2-yl}methanesulfonamide; cardiac arrhythmias KCNN2, KCNJ2, KCNH2 CYP1A2 1541/4885CYP2D6 401/4885HRH4 1497/4885
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 CYP1A2 3574/4885CYP2D6 3820/4885HRH4 1290/4885
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes SUN2, FDFT1, SIK1 CYP1A2 1760/4885CYP2D6 3004/4885HRH4 2770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.