Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022454 | 0.82 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL13696680 | 0.82 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL4780038 | 0.82 | PTGER4 (0.51) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL15280123 | 0.80 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL27985045 | 0.80 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL6483062 | 0.79 | CHRM2 (0.49) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL802084 | 0.79 | CDK1 (0.54) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL13932559 | 0.79 | CHRM2 (0.49) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL29357718 | 0.79 | CDK1 (0.54) | CHRM2CHRM4CHRM1CHRM3GABRG2 | |
| SCHEMBL28632028 | 0.79 | GABRG2 (0.65) | CHRM2CHRM4CHRM1CHRM3GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104231023-B | Tricyclic fused heterocycle nucleoside phosphoramidate compound, preparation method and application | 南京汇诚制药有限公司 | 2019-02-05 | — | — | CN | disclosed |