Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13696680 | 0.84 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL30022454 | 0.84 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL15280123 | 0.82 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL27985045 | 0.82 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL28278647 | 0.82 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL29357718 | 0.81 | CDK1 (0.54) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL6483062 | 0.81 | CHRM2 (0.49) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL28632028 | 0.81 | GABRG2 (0.65) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL13932559 | 0.81 | CHRM2 (0.49) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL802084 | 0.81 | CDK1 (0.54) | CHRM2CHRM4CHRM1CHRM3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |