SCHEMBL28279362

SCHEMBL28279362

CCCOC(=O)C1CCCC1OC(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
CHRM2 P08172 2/20 0.47
CHRM4 P08173 2/20 0.47
CHRM1 P11229 2/20 0.47
CHRM3 P20309 2/20 0.47
KCNH2 Q12809 1/20 0.45
ALDH1A1 P00352 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SLC18A3 Q16572 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28278032 0.97 LMNA (0.54) LMNACHRM2CHRM4CHRM1CHRM3
SCHEMBL28279416 0.93 KCNH2 (0.46) LMNACHRM2CHRM4CHRM1CHRM3
SCHEMBL28278041 0.91 CHRM2 (0.46) CHRM2CHRM4CHRM1CHRM3KCNH2
SCHEMBL28279402 0.90 KCNH2 (0.46) LMNACHRM2CHRM4CHRM1CHRM3
SCHEMBL28277997 0.90 KCNH2 (0.55) CHRM2CHRM4CHRM1CHRM3KCNH2
SCHEMBL28278397 0.89 CHRM2 (0.46) CHRM2CHRM4CHRM1CHRM3KCNH2
SCHEMBL28278031 0.87 KCNH2 (0.55) CHRM2CHRM4CHRM1CHRM3KCNH2
SCHEMBL2692166 0.82 HTR3E (0.54) CHRM2CHRM4CHRM1CHRM3KCNH2
SCHEMBL9696781 0.82 HTR3E (0.54) CHRM2CHRM4CHRM1CHRM3KCNH2
SCHEMBL28537112 0.77 LMNA (0.42) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN disclosed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN disclosed