Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.55 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541568 | 0.86 | HCAR3 (0.64) | MAPTPSMD14HCAR3WNK1ALDH1A1 | |
| SCHEMBL1924259 | 0.82 | HCAR3 (0.64) | MAPTPSMD14HCAR3WNK1ALDH1A1 | |
| SCHEMBL14754098 | 0.81 | HCAR3 (0.61) | MAPTPSMD14HCAR3WNK1ALDH1A1 | |
| SCHEMBL2728614 | 0.79 | HCAR3 (0.64) | MAPTHCAR3WNK1ALDH1A1LMNA | |
| SCHEMBL2341460 | 0.79 | HCAR3 (0.62) | MAPTPSMD14HCAR3WNK1ALDH1A1 | |
| SCHEMBL2033579 | 0.78 | MAPK1 (0.60) | MAPTHCAR3WNK1ALDH1A1LMNA | |
| SCHEMBL8884398 | 0.78 | ALDH1A1 (0.58) | MAPTHCAR3WNK1ALDH1A1LMNA | |
| SCHEMBL3874975 | 0.78 | ALDH1A1 (0.58) | MAPTHCAR3WNK1ALDH1A1LMNA | |
| SCHEMBL14050240 | 0.77 | HCAR3 (0.54) | MAPTHCAR3WNK1ALDH1A1LMNA | |
| SCHEMBL23786250 | 0.76 | MAPT (0.69) | MAPTHCAR3WNK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658643-B | IDO inhibitor | 百时美施贵宝公司 | 2019-03-01 | — | — | CN | disclosed |