SCHEMBL282802

SCHEMBL282802

Cc1cc(O)cc(C)c1N

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
CYP3A4 P08684 4/20 0.58
TDP1 Q9NUW8 3/20 0.58
TSHR P16473 2/20 0.58
TP53 P04637 2/20 0.58
ALOX15 P16050 2/20 0.52
CHRM1 P11229 1/20 0.52
MAOA P21397 1/20 0.52
TBXA2R P21731 1/20 0.52
ADRA1A P35348 1/20 0.52
HTR2B P41595 1/20 0.52
POLB P06746 1/20 0.48
BACE1 P56817 1/20 0.41
ACHE P22303 3/20 0.41
MEN1 O00255 1/20 0.41
HSP90AA1 P07900 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
GAA P10253 3/20 0.40
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1286281 0.86 CYP3A4 (0.46) ALDH1A1CYP3A4TDP1TSHRTP53
SCHEMBL1285581 0.86 CYP3A4 (0.46) ALDH1A1CYP3A4TDP1TSHRTP53
SCHEMBL18713987 0.82 CYP3A4 (0.42) ALDH1A1CYP3A4TDP1TSHRTP53
SCHEMBL3785424 0.82 CYP3A4 (0.54) ALDH1A1CYP3A4TDP1TSHRTP53
SCHEMBL11599328 0.78 LMNA (0.39) ALDH1A1CYP3A4TDP1TSHRTP53
SCHEMBL8409769 0.78 ALDH1A1 (0.49) ALDH1A1CYP3A4TDP1TSHRTP53
SCHEMBL13351383 0.78 CYP3A4 (0.39) ALDH1A1CYP3A4TDP1TSHRTP53
SCHEMBL16789778 0.77 CYP3A4 (0.38) ALDH1A1CYP3A4TDP1TSHRTP53
SCHEMBL15214028 0.77 KDM4E (0.47) ALDH1A1CYP3A4TDP1TSHRTP53
SCHEMBL17779280 0.77 KDM4E (0.47) ALDH1A1CYP3A4TDP1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362638-B Autocatalysis imide-ring-containing phthalonitrile resin and preparation method and application thereof 黑龙江省科学院石油化学研究院 2024-12-17 CN claimed
CN-113015935-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element using same 日产化学株式会社 2024-12-13 CN claimed
CN-118978553-A Heterometal binuclear catalyst based on Schiff base ligand and preparation method and application thereof 合肥工业大学 2024-11-19 CN claimed
CN-118955264-A Method for preparing p-benzoquinone compound by oxidizing aniline compound 浙江大学 2024-11-15 CN claimed
CN-113666826-B Aryl or heteroaryl methoxylation reaction method 五邑大学 2024-03-26 CN claimed
CN-117659337-A Environment-friendly polyurethane foam and preparation method thereof 徐州远博泡沫包装材料有限公司 2024-03-08 CN claimed
CN-117362638-A Autocatalysis imide-ring-containing phthalonitrile resin and preparation method and application thereof 黑龙江省科学院石油化学研究院 2024-01-09 CN claimed
CN-117164745-A Composite material for microporous membrane, composite ion exchange membrane and application of composite material 国家电投集团氢能科技发展有限公司 2023-12-05 CN claimed
CN-117126311-A Polymer, composite, ion exchange membrane and preparation method and application thereof 国家电投集团氢能科技发展有限公司 2023-11-28 CN claimed
CN-116808842-B Modified microporous membrane, composite ion exchange membrane, and preparation methods and applications thereof 国家电投集团氢能科技发展有限公司 2023-10-27 CN claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 US claimed
US-4865617-A Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers L'OREAL (FR) 1989-09-12 US claimed
US-4865618-A New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said L'OREAL (FR) 1989-09-12 US claimed
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 EP claimed
EP-0294669-A1 Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair L'OREAL (FR) 1988-12-14 EP claimed
US-4692166-A OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE L'OREAL (FR) 1987-09-08 US claimed
US-4425132-A HAIR DYES, APPLYING WITHOUT RINSING L'OREAL (FR) 1984-01-10 US claimed
US-4337061-A NITRO DYES IN AQUEOUS SOLUTION SOCIETE ANONYME DITE: L'OREAL (FR) 1982-06-29 US claimed
US-4200432-A HAIR DYES L'OREAL (FR) 1980-04-29 US claimed
US-3948596-A Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler SOCIETE ANONYME DITE: L'OREAL (FR) 1976-04-06 US claimed