SCHEMBL28280218

SCHEMBL28280218

CCCCCCCCCOC(=O)c1cccc(C)c1N

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.68
TSHR P16473 4/20 0.68
LMNA P02545 2/20 0.68
HSD17B10 Q99714 2/20 0.68
KDM4E B2RXH2 2/20 0.68
POLB P06746 1/20 0.68
CYP3A4 P08684 2/20 0.65
MAPK1 P28482 2/20 0.65
TP53 P04637 1/20 0.65
L3MBTL1 Q9Y468 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
MAPT P10636 2/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
CYP2D6 P10635 1/20 0.54
CYP19A1 P11511 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
ESR1 P03372 1/20 0.50
MMP2 P08253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28281254 1.00 ALDH1A1 (0.68) ALDH1A1TSHRLMNAHSD17B10KDM4E
SCHEMBL14645636 1.00 ALDH1A1 (0.68) ALDH1A1TSHRLMNAHSD17B10KDM4E
SCHEMBL28280186 1.00 ALDH1A1 (0.68) ALDH1A1TSHRLMNAHSD17B10KDM4E
SCHEMBL28077184 1.00 ALDH1A1 (0.68) ALDH1A1TSHRLMNAHSD17B10KDM4E
SCHEMBL14645882 0.99 TSHR (0.67) ALDH1A1TSHRLMNAHSD17B10KDM4E
SCHEMBL27519835 0.94 ALDH1A1 (0.66) ALDH1A1TSHRLMNAHSD17B10KDM4E
SCHEMBL15733096 0.94 CYP2D6 (0.59) ALDH1A1TSHRLMNAHSD17B10KDM4E
SCHEMBL19994754 0.88 ALDH1A1 (0.64) ALDH1A1TSHRLMNAHSD17B10KDM4E
SCHEMBL7145292 0.87 ALDH1A1 (0.78) ALDH1A1TSHRLMNAHSD17B10KDM4E
SCHEMBL7147146 0.87 ALDH1A1 (0.78) ALDH1A1TSHRLMNAHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN claimed
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN disclosed