Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28281254 | 0.99 | ALDH1A1 (0.68) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL28280186 | 0.99 | ALDH1A1 (0.68) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL28077184 | 0.99 | ALDH1A1 (0.68) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL14645636 | 0.99 | ALDH1A1 (0.68) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL28280218 | 0.99 | ALDH1A1 (0.68) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL27519835 | 0.95 | ALDH1A1 (0.66) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL15733096 | 0.92 | CYP2D6 (0.59) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL19994754 | 0.89 | ALDH1A1 (0.64) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL15733367 | 0.88 | CYP2D6 (0.67) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL7147146 | 0.85 | ALDH1A1 (0.78) | TSHRCYP3A4MAPK1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415553-B | Plasticized thermoset resins and related cured resins, curing methods, and articles comprising cured resins | 马萨诸塞大学 | 2022-08-05 | — | — | CN | claimed |
| EP-3481899-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | The University of Massachusetts (US) | 2019-05-15 | — | — | EP | claimed |
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | claimed |
| WO-2018008003-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | THE UNIVERSITY OF MASSACHUSETTS (US) | 2018-01-11 | — | — | WO | claimed |
| EP-3481899-B1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | UNIV MASSACHUSETTS (US) | 2022-12-21 | — | — | EP | disclosed |
| CN-109415553-B | Plasticized thermoset resins and related cured resins, curing methods, and articles comprising cured resins | 马萨诸塞大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-113396145-A | PFKFB3 inhibitors and uses thereof | 盖罗发现有限责任公司 | 2021-09-14 | — | — | CN | disclosed |
| US-10913844-B2 | Plasticized thermoset resin, and associated cured resin, method of curing, and article comprising cured resin | THE UNIVERSITY OF MASSACHUSETTS (US) | 2021-02-09 | — | — | US | disclosed |
| US-20190309159-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | THE UNIVERSITY OF MASSACHUSETTS | 2019-10-10 | — | — | US | disclosed |
| EP-3481899-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | The University of Massachusetts (US) | 2019-05-15 | — | — | EP | disclosed |
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-103702978-B | Process for preparing 2-amino-5-cyano-N, 3-dimethylbenzamide | 拜耳知识产权有限责任公司 | 2018-03-06 | — | — | CN | disclosed |
| WO-2018008003-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | THE UNIVERSITY OF MASSACHUSETTS (US) | 2018-01-11 | — | — | WO | disclosed |
| EP-2729444-B1 | METHOD FOR MANUFACTURING 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| US-9169198-B2 | Method for the production of 2-amino-5-cyano-N,3-dimethylbenzamide | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-20140148611-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-29 | — | — | US | disclosed |
| EP-2729444-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | Bayer Intellectual Property GmbH (DE) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013007603-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148611-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | ALKBH5, ALKBH2, MMAB | TSHR 4356/4885CYP3A4 438/4885MAPK1 3361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.