Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280201 | 0.95 | TSHR (0.58) | TSHRTDP1L3MBTL1TP53CYP3A4 | |
| SCHEMBL28866385 | 0.90 | ALDH1A1 (0.55) | TSHRTDP1L3MBTL1TP53CYP3A4 | |
| SCHEMBL14984028 | 0.90 | TSHR (0.68) | TSHRTDP1L3MBTL1TP53CYP3A4 | |
| SCHEMBL29860709 | 0.90 | TSHR (0.65) | TSHRTDP1L3MBTL1TP53CYP3A4 | |
| SCHEMBL17797782 | 0.86 | TSHR (0.66) | TSHRTDP1L3MBTL1TP53CYP3A4 | |
| SCHEMBL6057039 | 0.85 | TSHR (0.80) | TSHRTDP1L3MBTL1TP53CYP3A4 | |
| SCHEMBL28237720 | 0.85 | TSHR (0.59) | TSHRTDP1L3MBTL1TP53CYP3A4 | |
| SCHEMBL18669013 | 0.83 | TSHR (0.60) | TSHRTDP1L3MBTL1TP53CYP3A4 | |
| SCHEMBL8661935 | 0.83 | TSHR (0.81) | TSHRTDP1L3MBTL1TP53CYP3A4 | |
| SCHEMBL812415 | 0.83 | ALDH1A1 (0.55) | TSHRTDP1L3MBTL1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | claimed |
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | disclosed |