Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797782 | 0.89 | TSHR (0.66) | ALDH1A1TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL2655059 | 0.87 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL28866385 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL29860709 | 0.85 | TSHR (0.65) | ALDH1A1TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL14984028 | 0.85 | TSHR (0.68) | ALDH1A1TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL17681654 | 0.85 | TSHR (0.57) | ALDH1A1TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL28237720 | 0.84 | TSHR (0.59) | ALDH1A1TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL8433421 | 0.84 | TSHR (0.59) | ALDH1A1TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL17797867 | 0.84 | TSHR (0.59) | ALDH1A1TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL16049266 | 0.84 | TSHR (0.59) | ALDH1A1TSHRTDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968751-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7892518-B2 | fluorinating a specific position of a saccharide substrate selectively without affecting a protective group at a temperature within a wide range safely and easily with N, N-diethyl-alpha, alpha-difluoro(3-methyl)benzylamine a fluorinating agent under irradiation with microwave or electromagnetic wave | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-02-22 | — | — | US | disclosed |
| EP-2189467-A2 | Method of fluorination by microwaves | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2189466-A2 | METHOD OF FLUORINATION BY MICROWAVES | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-20080319228-A1 | Method of fluorination | HARA SHOJI | 2008-12-25 | — | — | US | disclosed |
| US-20080154064-A1 | Method of fluorination | HARA SHOJI | 2008-06-26 | — | — | US | disclosed |
| US-7351863-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20060014972-A1 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1568703-A1 | METHOD OF FLUORINATION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154064-A1 | Method of fluorination | FUCA2, FABP2, FGB | ALDH1A1 1770/4885TSHR 2253/4885TDP1 4196/4885 |
| US-20080319228-A1 | Method of fluorination | FUCA2, FABP2, FGB | ALDH1A1 1770/4885TSHR 2253/4885TDP1 4196/4885 |
| US-20060014972-A1 | Method of fluorination | FUCA2, FABP2, FGB | ALDH1A1 1770/4885TSHR 2253/4885TDP1 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.