Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL9441778 | 0.94 | ALDH1A1 (0.48) | ALDH1A1ALOX15RAB9AKCNN4NPC1 | |
| Fluorobenzene SCHEMBL5262143 | 0.89 | ALDH1A1 (0.44) | ALDH1A1ALOX15RAB9AKCNN4NPC1 | |
| Fluorobenzene SCHEMBL5865256 | 0.88 | KCNN4 (0.48) | ALDH1A1ALOX15RAB9AKCNN4NPC1 | |
| Fluorobenzene SCHEMBL28144868 | 0.88 | KCNN4 (0.48) | ALDH1A1ALOX15RAB9AKCNN4NPC1 | |
| Fluorobenzene SCHEMBL27550803 | 0.83 | ALDH1A1 (0.46) | ALDH1A1ALOX15RAB9AKCNN4NPC1 | |
| Fluorobenzene SCHEMBL5606691 | 0.82 | CES2 (0.46) | ALDH1A1ALOX15RAB9AKCNN4NPC1 | |
| Fluorobenzene SCHEMBL7243186 | 0.82 | CES2 (0.46) | ALDH1A1ALOX15RAB9AKCNN4NPC1 | |
| Fluorobenzene SCHEMBL10885260 | 0.82 | KCNN4 (0.56) | ALDH1A1RAB9AKCNN4NPC1MAPT | |
| Fluorobenzene SCHEMBL27399872 | 0.82 | KCNN4 (0.56) | ALDH1A1RAB9AKCNN4NPC1MAPT | |
| Fluorobenzene SCHEMBL14012524 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431422-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2019-08-30 | — | — | CN | disclosed |
| CN-109456324-A | New isoindoline or isoquinoline compound, preparation method and the Pharmaceutical composition containing them | 法国施维雅药厂 | 2019-03-12 | — | — | CN | disclosed |