Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936117 | 0.89 | RAB9A (0.62) | RAB9ADPP7GAALMNAFDPS | |
| SCHEMBL4936105 | 0.89 | RAB9A (0.62) | RAB9ADPP7GAALMNAFDPS | |
| SCHEMBL4940630 | 0.86 | RAB9A (0.64) | RAB9ADPP7GAALMNATP53 | |
| SCHEMBL4940641 | 0.86 | RAB9A (0.64) | RAB9ADPP7GAALMNATP53 | |
| SCHEMBL26986914 | 0.84 | DPP7 (0.48) | RAB9ADPP7GAALMNAFDPS | |
| SCHEMBL1503488 | 0.81 | DPP7 (0.48) | RAB9ADPP7GAALMNAFDPS | |
| SCHEMBL472306 | 0.80 | DPP7 (0.42) | RAB9ADPP7GAALMNAFDPS | |
| SCHEMBL28912998 | 0.79 | RAB9A (0.47) | RAB9ATP53SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28679629 | 0.79 | RAB9A (0.47) | RAB9ADPP7TP53FDPSKMT2A | |
| SCHEMBL28676131 | 0.79 | RAB9A (0.47) | RAB9ADPP7TP53FDPSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108138177-B | The combination of Dbait molecule and PARP inhibitor is used for the purposes for the treatment of cancer | 法国居里学院 | 2019-03-19 | — | — | CN | disclosed |