Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetoacetic Acid SCHEMBL27487797 | 0.81 | KDM4E (0.41) | POLBKDM4EKDM6BKDM5CEGLN1 | |
| Acetoacetic Acid SCHEMBL27575710 | 0.80 | LMNA (0.50) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL7681046 | 0.80 | — | — | |
| SCHEMBL569588 | 0.80 | — | — | |
| Acetoacetic Acid SCHEMBL27528835 | 0.79 | TSHR (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL25658325 | 0.78 | POLB (0.50) | POLBKDM4EKDM6BKDM5CEGLN1 | |
| Acetoacetic Acid SCHEMBL27542056 | 0.78 | KDM4E (0.46) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| Glutarate SCHEMBL31083839 | 0.77 | SLC22A6 (0.50) | POLBLMNATSHRALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL8593625 | 0.77 | — | — | |
| Acetoacetic Acid SCHEMBL10941648 | 0.77 | LDHA (0.57) | KDM4EKDM6BKDM5CEGLN1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574945-A | Isoxazoline derivative and its application in agricultural | 东莞东阳光科研发有限公司 | 2019-04-05 | — | — | CN | disclosed |