Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820120 | 0.91 | HDAC8 (0.58) | GRM5HDAC8FFAR1PIK3CAMTOR | |
| SCHEMBL1649302 | 0.88 | HDAC8 (0.55) | GRM5HDAC8FFAR1CHRM2SIGMAR1 | |
| SCHEMBL13907339 | 0.82 | HDAC8 (0.50) | GRM5HDAC8FFAR1CHRM2SIGMAR1 | |
| SCHEMBL13907329 | 0.82 | HDAC8 (0.50) | GRM5HDAC8FFAR1PIK3CAMTOR | |
| SCHEMBL17378288 | 0.81 | GRM5 (0.61) | GRM5HDAC8FFAR1CHRM2SIGMAR1 | |
| SCHEMBL3270303 | 0.81 | APP (0.56) | GRM5HDAC8FFAR1CHRM2SIGMAR1 | |
| SCHEMBL2925968 | 0.80 | APP (0.67) | GRM5HDAC8FFAR1PIK3CAMTOR | |
| SCHEMBL7690758 | 0.80 | — | — | |
| SCHEMBL9610040 | 0.80 | MAPT (0.53) | GRM5HDAC8FFAR1PIK3CAMTOR | |
| SCHEMBL21652624 | 0.79 | GRM5 (0.50) | GRM5HDAC8FFAR1CHRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109420480-A | A kind of separation method of C 4 olefin mixture | 浙江大学 | 2019-03-05 | — | — | CN | disclosed |