Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28284101 | 0.80 | SMN1; SMN2 (0.33) | GAAHTTTSHR | |
| SCHEMBL18793295 | 0.78 | MEN1 (0.32) | GAAMEN1KMT2ALMNATSHR | |
| SCHEMBL19978996 | 0.78 | MEN1 (0.32) | GAAMEN1KMT2ALMNATSHR | |
| SCHEMBL28304605 | 0.75 | DRD4 (0.37) | ALDH1A1GAAMAPTHTTLMNA | |
| SCHEMBL20738490 | 0.75 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL29649295 | 0.75 | UGT2B17 (0.39) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL4421275 | 0.75 | CYP11B1 (0.32) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30125519 | 0.73 | CYP11B1 (0.31) | MEN1KMT2A | |
| SCHEMBL19642859 | 0.73 | KMT2A (0.35) | GAAMAPTHTTKMT2ALMNA | |
| SCHEMBL19656906 | 0.73 | LMNA (0.35) | ALDH1A1GAAHTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689663-A | The two ring inhibitor of spiral shell of MENIN-MLL interaction | 詹森药业有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109475530-A | For treating the aminoacyl indazole immunomodulator of autoimmune disease | 洛克菲勒大学 | 2019-03-15 | — | — | CN | disclosed |