Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280853 | 0.80 | ALDH1A1 (0.32) | HTTTSHRGAA | |
| SCHEMBL28304605 | 0.66 | DRD4 (0.37) | SMN1; SMN2HTTTSHRGAA | |
| SCHEMBL17682605 | 0.65 | HTT (0.54) | SMN1; SMN2RAB9ANPC1HTTHPGD | |
| SCHEMBL27583234 | 0.65 | DRD2 (0.33) | — | |
| SCHEMBL10192403 | 0.64 | ELANE (0.48) | SMN1; SMN2RAB9ANPC1HTTHPGD | |
| SCHEMBL28456930 | 0.64 | F12 (0.34) | — | |
| SCHEMBL28172969 | 0.64 | PDE10A (0.33) | — | |
| SCHEMBL27707713 | 0.63 | — | — | |
| SCHEMBL27497235 | 0.63 | CYP19A1 (0.48) | — | |
| SCHEMBL27827789 | 0.63 | CYP19A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574936-A | A kind of hydroxamic acid compound and its application with HDAC6 inhibitory activity | 沈阳药科大学 | 2019-04-05 | — | — | CN | disclosed |