Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3248430 | 0.91 | ALDH1A1 (0.50) | KMT2AMEN1CA1CA2SMN1; SMN2 | |
| SCHEMBL3248426 | 0.91 | ALDH1A1 (0.50) | KMT2AMEN1CA1CA2SMN1; SMN2 | |
| SCHEMBL5500086 | 0.81 | KMT2A (0.55) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL567435 | 0.80 | MEN1 (0.55) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL10885861 | 0.79 | MEN1 (0.53) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL27791880 | 0.78 | MEN1 (0.56) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL4707157 | 0.78 | MEN1 (0.52) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL6154376 | 0.77 | MEN1 (0.55) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL6154384 | 0.77 | MEN1 (0.55) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL28281127 | 0.77 | KMT2A (0.51) | KMT2AMEN1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415355-A | Benzdioxan derivative and its medicinal usage | 奥赖恩公司 | 2019-03-01 | — | — | CN | disclosed |