Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831241 | 0.84 | MAPK1 (0.46) | MAPK1MEN1MAPTKMT2AATM | |
| SCHEMBL2789076 | 0.82 | CTNNB1 (0.51) | MAPK1MEN1MAPTKMT2AATM | |
| SCHEMBL4255993 | 0.80 | MAPK1 (0.50) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL16675476 | 0.79 | MAPK1 (0.49) | MAPK1MEN1KMT2ALMNAATM | |
| SCHEMBL28864004 | 0.77 | ATM (0.52) | MAPK1MEN1MAPTKMT2AATM | |
| SCHEMBL15245639 | 0.76 | MAPK1 (0.47) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL2582219 | 0.76 | MEN1 (0.52) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL27609985 | 0.76 | ATM (0.44) | MAPK1MEN1MAPTKMT2AHTT | |
| SCHEMBL7022975 | 0.75 | ATM (0.50) | MAPK1MEN1MAPTKMT2AATM | |
| SCHEMBL14694211 | 0.75 | ATM (0.50) | MAPK1MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300230-B | N-(hetero) aryl indole derivatives as pesticides | NOVARTIS AG | 2011-04-13 | — | — | CN | disclosed |
| EP-1945611-B1 | N- (HETERO) ARYL INDOLE DERIVATIVES AS PESTICIDES | NOVARTIS AG (CH) | 2010-01-06 | — | — | EP | disclosed |
| US-20090227538-A1 | N-(Hetero)Aryl Indole Derivatives as Pesticides | NOVARTIS AG (CH) | 2009-09-10 | — | — | US | disclosed |
| CN-101300230-A | N-(hetero) aryl indole derivatives as pesticides | NOVARTIS AG (CH) | 2008-11-05 | — | — | CN | disclosed |
| EP-1783114-A1 | N-(hetero)aryl indole derivatives as pesticides | Novartis AG (CH) | 2007-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227538-A1 | N-(Hetero)Aryl Indole Derivatives as Pesticides | IDO1, IDO2, CHRM1 | MAPK1 3888/4885MEN1 2044/4885MAPT 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.