Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2828189 | 0.84 | MAPK1 (0.50) | MAPK1ATMPBRM1CTNNB1WNT3A | |
| SCHEMBL27719429 | 0.78 | ATM (0.43) | MAPK1ATMPBRM1CTNNB1WNT3A | |
| SCHEMBL16394486 | 0.78 | CYP2A6 (0.43) | GPR84NR4A2 | |
| SCHEMBL16675476 | 0.78 | MAPK1 (0.49) | MAPK1ATMPBRM1CTNNB1WNT3A | |
| SCHEMBL799601 | 0.77 | ATM (0.54) | MAPK1ATMPBRM1GPR84AHR | |
| SCHEMBL13335152 | 0.77 | ATM (0.54) | MAPK1ATMPBRM1GPR84AHR | |
| SCHEMBL2789076 | 0.77 | CTNNB1 (0.51) | MAPK1ATMCTNNB1WNT3AGPR84 | |
| SCHEMBL1685393 | 0.77 | ATM (0.54) | MAPK1ATMPBRM1GPR84AHR | |
| SCHEMBL30437029 | 0.77 | ATM (0.54) | MAPK1ATMPBRM1GPR84AHR | |
| SCHEMBL29885789 | 0.77 | ATM (0.54) | MAPK1ATMPBRM1GPR84AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945611-B1 | N- (HETERO) ARYL INDOLE DERIVATIVES AS PESTICIDES | NOVARTIS AG (CH) | 2010-01-06 | — | — | EP | disclosed |
| US-20090227538-A1 | N-(Hetero)Aryl Indole Derivatives as Pesticides | NOVARTIS AG (CH) | 2009-09-10 | — | — | US | disclosed |
| EP-1783114-A1 | N-(hetero)aryl indole derivatives as pesticides | Novartis AG (CH) | 2007-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227538-A1 | N-(Hetero)Aryl Indole Derivatives as Pesticides | IDO1, IDO2, CHRM1 | MAPK1 3888/4885ATM 3649/4885PBRM1 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.