SCHEMBL9580484

SCHEMBL9580484

COc1ccc(/C=C/c2ccc(C(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.69
BCHE P06276 1/20 0.69
NFKB1 P19838 1/20 0.69
NFKB2 Q00653 1/20 0.69
RELA Q04206 1/20 0.69
TRPA1 O75762 1/20 0.67
MAPT P10636 3/20 0.64
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
ALDH1A1 P00352 2/20 0.64
HSPD1 P10809 1/20 0.64
TNFRSF1A P19438 1/20 0.64
MAOB P27338 1/20 0.64
HSPE1 P61604 1/20 0.64
CYP1B1 Q16678 1/20 0.64
SNCA P37840 2/20 0.63
CES2 O00748 1/20 0.62
CES1 P23141 1/20 0.62
F3 P13726 2/20 0.60
THRB P10828 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9580489 1.00 CYP3A4 (0.69) CYP3A4BCHENFKB1NFKB2RELA
SCHEMBL25954596 0.93 F3 (0.68) CYP3A4RELATRPA1MAPTMEN1
SCHEMBL50261 0.89 CES2 (0.77) MAPTMEN1KMT2AALDH1A1CES2
SCHEMBL6618691 0.89 CES2 (0.77) MAPTMEN1KMT2AALDH1A1CES2
Benzophenone SCHEMBL27935236 0.89 CES2 (0.77) MAPTMEN1KMT2AALDH1A1CES2
Benzophenone SCHEMBL28282178 0.89 THRB (0.78) CYP3A4BCHENFKB1NFKB2RELA
SCHEMBL28888786 0.87 CES2 (0.74) MAPTMEN1KMT2AALDH1A1CES2
Hydrochloric Acid SCHEMBL4595093 0.87 CES2 (0.74) MAPTMEN1KMT2AALDH1A1CES2
SCHEMBL28393149 0.87 CES2 (0.74) MAPTMEN1KMT2AALDH1A1CES2
Hydrochloric Acid SCHEMBL4595086 0.87 CES2 (0.74) MAPTMEN1KMT2AALDH1A1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993001173-A1 PRODUCTION OF AROMATIC OLEFINS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1993-01-21 WO disclosed