Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699016 | 0.86 | CA1 (0.44) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL28733500 | 0.86 | HTT (0.47) | HTR6KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL29428840 | 0.73 | HTR6 (0.46) | HTR6KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL6421682 | 0.71 | HTR6 (0.47) | HTR6KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL28901979 | 0.70 | HTR6 (0.46) | HTR6KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL29428770 | 0.69 | CYP2C19 (0.44) | HTR6KMT2AMEN1ALDH1A1DCTPP1 | |
| SCHEMBL2273205 | 0.69 | CYP2C19 (0.44) | HTR6KMT2AMEN1ALDH1A1DCTPP1 | |
| SCHEMBL20762623 | 0.69 | HTR6 (0.53) | HTR6KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL29687030 | 0.69 | HTR6 (0.61) | HTR6KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL3241536 | 0.69 | HTR6 (0.61) | HTR6KMT2AMEN1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323612-A | Tricyclic urea compounds as JAK 2V 617F inhibitors | 因赛特公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116234550-A | Aromatic formyl substituted tricyclic compound and preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115403581-B | Heterocyclic compounds as IRAK4 inhibitors | 英矽智能科技(上海)有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115403581-A | Novel heterocyclic compounds as IRAK4 inhibitors | 英矽智能科技(上海)有限公司 | 2022-11-29 | — | — | CN | disclosed |
| WO-2022063101-A1 | AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-03-31 | — | — | WO | disclosed |
| CN-108715590-B | Thiazolecarboxamide and picolinamide compounds useful as PIM kinase inhibitors | 因赛特公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-109535164-A | JAK kinase inhibitor, preparation method thereof and application thereof in medical field | 上海华汇拓医药科技有限公司 | 2019-03-29 | — | — | CN | disclosed |