Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENO1 | P06733 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5406487 | 0.88 | RAB9A (0.30) | RAB9A | |
| SCHEMBL10770001 | 0.81 | HSD17B10 (0.33) | ENO1FKBP1ALMNACYP2C19HSD17B10 | |
| SCHEMBL28188099 | 0.78 | MEN1 (0.45) | ENO1FKBP1ALMNACYP2C19HSD17B10 | |
| SCHEMBL27801797 | 0.77 | FKBP1A (0.36) | FKBP1ALMNACYP2C19HSD17B10 | |
| SCHEMBL10769997 | 0.76 | HSD17B10 (0.33) | ENO1LMNACYP2C19HSD17B10 | |
| SCHEMBL28021974 | 0.76 | HSD17B10 (0.33) | ENO1LMNACYP2C19HSD17B10 | |
| SCHEMBL28021961 | 0.76 | HSD17B10 (0.33) | ENO1LMNACYP2C19HSD17B10 | |
| SCHEMBL28870856 | 0.72 | POLB (0.32) | ENO1FKBP1ALMNACYP2C19HSD17B10 | |
| SCHEMBL28284120 | 0.72 | POLB (0.32) | ENO1FKBP1ALMNACYP2C19HSD17B10 | |
| SCHEMBL5406197 | 0.72 | HSD17B10 (0.52) | LMNAHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476658-A | Substituted 5,6,7,8- tetrahydro [1,2,4] triazol [4,3-A] pyridine -3 (2H) -one and 2,5,6,7- tetrahydro -3H- pyrrolo- [2,1-c] [1,2,4] triazole -3- ketone and application thereof | 拜耳公司 | 2019-03-15 | — | — | CN | disclosed |