Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724891 | 0.98 | BID (0.44) | TLR8BIDMCL1PPARABCL2L1 | |
| SCHEMBL14917466 | 0.84 | NOS2 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27843475 | 0.84 | BID (0.44) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL27917301 | 0.84 | BID (0.44) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL2359608 | 0.84 | BID (0.44) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL28972407 | 0.82 | BID (0.47) | TLR8BIDMCL1PPARABCL2L1 | |
| SCHEMBL28284489 | 0.80 | GABRP (0.39) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL9206932 | 0.80 | GABRP (0.39) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL28972378 | 0.78 | BRD4 (0.43) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL27827785 | 0.76 | TYR (0.43) | TLR8BIDMCL1PPARABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061967-B | The nicotinamide compounds replaced through heteroaryl | 百时美施贵宝公司 | 2019-04-19 | — | — | CN | claimed |