Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234 | 0.81 | TP53 (0.36) | TSHRALDH1A1THPO | |
| SCHEMBL7029457 | 0.81 | TSHR (0.38) | TSHRALDH1A1THPO | |
| SCHEMBL2012306 | 0.80 | TSHR (0.35) | TSHRELANE | |
| SCHEMBL886971 | 0.79 | TSHR (0.32) | TSHRALDH1A1 | |
| SCHEMBL3647936 | 0.79 | TSHR (0.52) | TSHRALDH1A1 | |
| SCHEMBL16250 | 0.78 | TSHR (0.42) | TSHRALDH1A1ELANE | |
| SCHEMBL2337629 | 0.78 | TSHR (0.33) | TSHRELANE | |
| SCHEMBL4221918 | 0.78 | TSHR (0.33) | TSHRELANE | |
| SCHEMBL186118 | 0.77 | — | — | |
| SCHEMBL3483590 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109554396-B | Imidazole derivative and gene delivery system thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-109554396-A | A kind of imdazole derivatives and its gene pass release system | 复旦大学 | 2019-04-02 | — | — | CN | disclosed |