SCHEMBL8234

SCHEMBL8234

CC(=O)C(=O)OC(=O)C(C)O

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
TSHR P16473 4/20 0.33
ALDH1A1 P00352 1/20 0.32
THPO P40225 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9435540 0.86 TP53 (0.42) TP53TSHRALDH1A1
SCHEMBL6072620 0.80 TSHR (0.50) TP53TSHRALDH1A1
SCHEMBL447234 0.80 TP53 (0.47) TP53TSHRALDH1A1
SCHEMBL8163675 0.78 TP53 (0.32) TP53TSHR
SCHEMBL8975401 0.78 TSHR (0.31) TSHR
SCHEMBL1018572 0.78
SCHEMBL31019979 0.77 TP53 (0.44) TP53TSHRALDH1A1
SCHEMBL28763748 0.77 TP53 (0.44) TP53TSHRALDH1A1
SCHEMBL371443 0.77 TP53 (0.44) TP53TSHRALDH1A1
SCHEMBL2131856 0.77 TP53 (0.44) TP53TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113271931-A New application of carbamate beta phenylethanolamine analogue in enhancing clearance of intracellular LDL cholesterol and combination with statins 谭文 2021-08-17 CN claimed
CN-109280032-A A kind of histon deacetylase (HDAC) inhibitor and its preparation method and application of pyridazinone mother nucleus structure 中国科学院上海药物研究所 2019-01-29 CN claimed
CN-101579625-A Catalyst and reaction process for preparing pyruvic acid by lactic acid in catalytic oxydehydrogenation way UNIV HUNAN (CN) 2009-11-18 CN claimed
US-20240238255-A1 KL1333 FOR USE IN MEDICINE YUNGJIN PHARM. CO., LTD (KR) 2024-07-18 US disclosed
US-12012437-B2 Methods of treating mitochondrial disorders THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-18 US disclosed
CN-114732007-B Sperm cell process, apparatus and related media compositions 英格朗公司 2024-04-12 CN disclosed
EP-4350323-A2 SYSTEM FOR PREPARING AN OUTPUT SAMPLE COMPRISING A DEFINED CONCENTRATION OF AN INFECTIOUS AGENT FOR DOWNSTREAM TESTING Avails Medical, Inc. (US) 2024-04-10 EP disclosed
EP-3968021-B1 SYSTEM FOR PREPARING AN OUTPUT SAMPLE COMPRISING A DEFINED CONCENTRATION OF AN INFECTIOUS AGENT FOR DOWNSTREAM TESTING AVAILS MED INC (US) 2024-04-03 EP disclosed
EP-4340831-A1 KL1333 FOR USE IN MEDICINE Abliva AB (SE) 2024-03-27 EP disclosed
CN-117597429-A Method and system for assessing the quality of flow dynamics in sperm-containing samples 康奈尔大学 2024-02-23 CN disclosed
US-20240042440-A1 METHODS FOR EVALUATING RHEOTAXIS QUALITY IN A SPERM-CONTAINING SAMPLE AND SYSTEMS THEREFOR CORNELL UNIVERSITY 2024-02-08 US disclosed
US-4445500-A Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders THOMAS JEFFERSON UNIVERSITY (US) 1984-05-01 US disclosed
US-4353867-A COMPUTERIZED QUANTITATIVE ANALYZER LUZZANA MASSIMO 1982-10-12 US disclosed
EP-0052718-A1 Method and apparatus for the determination of substances in biological solutions by differential pH measurement Luzzana, Massimo (IT) 1982-06-02 EP disclosed
US-4282325-A FOR AMPLIFICATION IN ASSAYS SYVA COMPANY (US) 1981-08-04 US disclosed
US-4203802-A ENZYME BOUND TO AN ESTROGEN LIGAND SYVA COMPANY (US) 1980-05-20 US disclosed
US-4190496-A RECEPTOR, LIGAND, AND ENZYME-BOUND SYVA COMPANY (US) 1980-02-26 US disclosed
US-4067774-A Compounds for enzyme amplification assay SYVA COMPANY (US) 1978-01-10 US disclosed
US-3975237-A LIGANDS SYVA COMPANY (US) 1976-08-17 US disclosed
US-3966556-A Compounds for enzyme amplification assay methadone analogs SYVA COMPANY (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238255-A1 KL1333 FOR USE IN MEDICINE CKMT1A; CKMT1B, SLC25A1, MT-ND3 TP53 2722/4885TSHR 2627/4885ALDH1A1 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.