Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732516 | 0.83 | KDR (0.53) | LOXL2KDRCHEK1RAB9AKDM4E | |
| SCHEMBL27491417 | 0.83 | FFAR1 (0.59) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL6924193 | 0.82 | KDM4E (0.57) | LOXL2KDRCHEK1RAB9AKDM4E | |
| SCHEMBL5051826 | 0.81 | KDR (0.68) | LOXL2KDRCHEK1RAB9AKDM4E | |
| SCHEMBL10832168 | 0.80 | RAB9A (0.51) | KDRCHEK1RAB9AKDM4EMAPT | |
| Methane SCHEMBL28704887 | 0.79 | KDR (0.66) | LOXL2KDRCHEK1RAB9AKDM4E | |
| Benzene SCHEMBL27629233 | 0.79 | RAB9A (0.69) | LOXL2KDRCHEK1RAB9AKDM4E | |
| SCHEMBL11785543 | 0.79 | KDM4E (0.49) | LOXL2KDRCHEK1RAB9AKDM4E | |
| SCHEMBL30832959 | 0.79 | KDR (0.53) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL21481532 | 0.78 | DPP4 (0.40) | LOXL2RAB9AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920775-B | Axial chiral bisindole catalyst and synthetic method and application thereof | 江苏师范大学 | 2023-08-04 | — | — | CN | claimed |
| CN-101935297-B | 3,3- diindolyl derivative and preparation method thereof | UNIV ZHEJIANG | 2012-09-05 | — | — | CN | claimed |
| CN-101935297-A | 3,3- diindolyl derivative and preparation method thereof | UNIV ZHEJIANG | 2011-01-05 | — | — | CN | claimed |
| CN-114920775-B | Axial chiral bisindole catalyst and synthetic method and application thereof | 江苏师范大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-114920775-B | Axial chiral bisindole catalyst and synthetic method and application thereof | 江苏师范大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-114920775-A | Axial chiral bisindole catalyst and synthesis method and application thereof | 江苏师范大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-109575033-A | The method of level-one amine guiding building 6- (2- aminomethyl phenyl) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-101935297-B | 3,3- diindolyl derivative and preparation method thereof | UNIV ZHEJIANG | 2012-09-05 | — | — | CN | disclosed |
| CN-101935297-A | 3,3- diindolyl derivative and preparation method thereof | UNIV ZHEJIANG | 2011-01-05 | — | — | CN | disclosed |