Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283441 | 0.82 | LOXL2 (0.53) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL27491417 | 0.73 | FFAR1 (0.59) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| 2-(2'-Methoxyphenyl)-1H-Indole SCHEMBL5634916 | 0.73 | KDM4E (1.00) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| 2-(2'-Methoxyphenyl)-1H-Indole SCHEMBL31053096 | 0.73 | KDM4E (1.00) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL6503170 | 0.73 | RAB9A (0.57) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL5051826 | 0.72 | KDR (0.68) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL16428829 | 0.71 | DPP4 (0.60) | RAB9AF2F10PLGPLAU | |
| SCHEMBL21484073 | 0.70 | RAB9A (0.47) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL10176240 | 0.70 | KDR (0.61) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL8732516 | 0.70 | KDR (0.53) | KDM4EMAPTRAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040038943-A1 | Indole and benzimidazole 15-lipoxygenase inhibitors | CONNOR DAVID THOMAS (US) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038943-A1 | Indole and benzimidazole 15-lipoxygenase inhibitors | ALOX15, ALOX5, ALOX12 | KDM4E 881/4885MAPT 4865/4885RAB9A 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.