SCHEMBL28284033

SCHEMBL28284033

COC(=O)C(=CC1CCCCC1)C(F)(F)F

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.33
PDK2 Q15119 1/20 0.33
PDK3 Q15120 1/20 0.33
PDK4 Q16654 1/20 0.33
EPHX2 P34913 2/20 0.33
NPSR1 Q6W5P4 1/20 0.32
CYP3A4 P08684 1/20 0.32
GRIK1 P39086 1/20 0.31
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13858138 0.91 ALDH1A1 (0.32) MAPT
SCHEMBL27608400 0.84 EPHX2 (0.33) PDK1PDK2PDK3PDK4EPHX2
SCHEMBL8078029 0.80 EPHX1 (0.33) EPHX2NPSR1
SCHEMBL27706197 0.78 NPSR1 (0.35) EPHX2NPSR1CYP3A4GRIK1MAPT
SCHEMBL15913809 0.76 NPSR1 (0.36) EPHX2NPSR1GRIK1MAPT
SCHEMBL25410634 0.74 NPSR1 (0.35) EPHX2NPSR1GRIK1MAPT
SCHEMBL639052 0.74 NPSR1 (0.35) EPHX2NPSR1GRIK1MAPT
SCHEMBL17159432 0.74 NPSR1 (0.35) EPHX2NPSR1GRIK1MAPT
SCHEMBL5388557 0.74 NPSR1 (0.35) EPHX2NPSR1GRIK1MAPT
SCHEMBL28178766 0.74 NPSR1 (0.35) EPHX2NPSR1GRIK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476774-A Polymeric materials using controlled free radical initiators and methods of making 3M创新有限公司 2019-03-15 CN disclosed