Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28284033 | 0.91 | PDK1 (0.33) | MAPT | |
| SCHEMBL13858241 | 0.75 | GRIK1 (0.31) | — | |
| SCHEMBL15915880 | 0.75 | GRIK1 (0.31) | — | |
| SCHEMBL15915882 | 0.75 | GRIK1 (0.31) | — | |
| SCHEMBL18655700 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL27608400 | 0.74 | EPHX2 (0.33) | — | |
| SCHEMBL9421764 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4007809 | 0.73 | RECQL (0.35) | ALDH1A1MAPT | |
| SCHEMBL5532962 | 0.71 | ALDH1A1 (0.35) | ALDH1A1MAPT | |
| SCHEMBL20042556 | 0.71 | ALDH1A1 (0.35) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158795-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS TYROSINE KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2012-11-22 | — | — | WO | disclosed |