Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28139129 | 0.84 | POLB (0.62) | POLBRAB9ANPC1LMNAMAPT | |
| SCHEMBL28236651 | 0.83 | POLB (0.49) | POLBRAB9ANPC1LMNAMAPT | |
| SCHEMBL9723990 | 0.78 | POLB (0.56) | POLBRAB9ANPC1LMNAMAPT | |
| SCHEMBL27324256 | 0.78 | POLB (0.56) | POLBRAB9ANPC1LMNAMAPT | |
| SCHEMBL9269046 | 0.78 | POLB (0.56) | POLBRAB9ANPC1LMNAMAPT | |
| SCHEMBL59309 | 0.78 | RAB9A (0.61) | POLBRAB9ANPC1LMNAMAPT | |
| SCHEMBL29363181 | 0.78 | RAB9A (0.61) | POLBRAB9ANPC1LMNAMAPT | |
| SCHEMBL2223774 | 0.78 | NPC1 (0.43) | POLBRAB9ANPC1LMNAMAPT | |
| Alcohol SCHEMBL6573170 | 0.77 | NPC1 (0.57) | POLBRAB9ANPC1LMNAMAPT | |
| SCHEMBL27738652 | 0.77 | POLB (0.43) | POLBRAB9ANPC1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104620137-B | With the less viscous high refractive index ophthalmic device materials of drop | 诺华股份有限公司 | 2019-04-09 | — | — | CN | disclosed |