Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023997 | 0.82 | AR (0.54) | ARPGRPOLBGAA | |
| SCHEMBL25983090 | 0.80 | AR (0.46) | ARPGR | |
| SCHEMBL28569048 | 0.78 | POLB (0.49) | ARPOLBGAA | |
| SCHEMBL22342513 | 0.74 | AR (0.54) | ARPOLBGAA | |
| SCHEMBL5514386 | 0.74 | AR (0.38) | ARPGR | |
| SCHEMBL5509413 | 0.74 | HTR1A (0.42) | ARPGR | |
| SCHEMBL27960917 | 0.74 | GAA (0.50) | ARPOLBGAA | |
| SCHEMBL4604160 | 0.73 | FNTA (0.43) | AR | |
| SCHEMBL1994873 | 0.73 | AR (0.41) | ARPGR | |
| SCHEMBL29378798 | 0.73 | AR (0.41) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422737-A | Imidazolone androgen receptor antagonists, preparation method and use | 上海时莱生物技术有限公司 | 2019-03-05 | — | — | CN | disclosed |