Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.43 |
| ▸ | FNTB | P49356 | 3/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957296 | 0.83 | FNTA (0.52) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL22784142 | 0.80 | MAOB (0.54) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL28569048 | 0.76 | POLB (0.49) | ARALDH1A1 | |
| SCHEMBL5509413 | 0.75 | HTR1A (0.42) | ARMAOAALDH1A1 | |
| SCHEMBL7078940 | 0.74 | FNTA (0.54) | FNTAFNTBPGGT1BMAOAMAOB | |
| SCHEMBL1154474 | 0.74 | CYP11B1 (0.43) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL28285016 | 0.73 | AR (0.40) | AR | |
| SCHEMBL31023997 | 0.73 | AR (0.54) | ARMAOAMAOB | |
| SCHEMBL6960881 | 0.73 | NAAA (0.56) | FNTAFNTBPGGT1BMAOAMAOB | |
| SCHEMBL6960554 | 0.73 | NAAA (0.56) | FNTAFNTBPGGT1BMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915338-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007017754-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-15 | — | — | WO | disclosed |