SCHEMBL28285285

SCHEMBL28285285

[CH2]c1cccc([CH]C(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18378693 0.76 TP53 (0.56) TP53TDP1
SCHEMBL22438758 0.75
SCHEMBL18243444 0.74 CHRM5 (0.52)
SCHEMBL18243495 0.74 NFE2L2 (0.58)
SCHEMBL18242502 0.74 ALDH1A1 (0.54)
SCHEMBL18378053 0.74 APP (0.46) TP53TDP1
SCHEMBL14157350 0.74 TYR (0.42) TP53TDP1
SCHEMBL1176403 0.74 CYP19A1 (0.52) TP53TDP1
SCHEMBL316960 0.72
SCHEMBL611292 0.71 CNR2 (0.42) TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109666022-A Triazole derivatives and its preparation method and application 中国科学院上海药物研究所 2019-04-23 CN disclosed