Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A known ✓ | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A known ✓ | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A known ✓ | Q9NY46 | 2/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.41 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.41 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28209306 | 0.94 | TSHR (0.59) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| Acetic Acid SCHEMBL28318749 | 0.92 | TSHR (0.57) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| Sulfuric Acid SCHEMBL27302890 | 0.79 | ALDH1A1 (0.87) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL23332021 | 0.78 | TSHR (0.69) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| Sulfuric Acid SCHEMBL28123758 | 0.77 | ALDH1A1 (0.84) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL28313448 | 0.77 | ALDH1A1 (0.68) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL3805742 | 0.76 | TSHR (0.78) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL30173476 | 0.76 | TSHR (0.78) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| Dibutyl Phthalate SCHEMBL28178647 | 0.76 | TSHR (0.86) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL11349185 | 0.75 | TSHR (0.59) | TSHRMAPK1CYP3A4TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104276962-B | A kind of aspirin derivatives and combinations thereof and application | 浙江越甲药业有限公司 | 2019-04-12 | — | — | CN | disclosed |