SCHEMBL28286186

SCHEMBL28286186

CCC(OCC1CO1)[Si](C)(C)N

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 7/20 0.41
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 2/20 0.34
MAPK1 P28482 1/20 0.34
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1035031 0.84 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL3462781 0.81 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1059012 0.81 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL29152791 0.81 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1058466 0.81 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL329862 0.81 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL29104566 0.81 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL28307977 0.81 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL23673323 0.79 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL28764 0.79 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109722661-A Rear-earth-doped inorganic agent of a kind of basic silane for Treatment of Metal Surface and its preparation method and application 沈阳帕卡濑精有限总公司 2019-05-07 CN claimed
CN-109722661-A Rear-earth-doped inorganic agent of a kind of basic silane for Treatment of Metal Surface and its preparation method and application 沈阳帕卡濑精有限总公司 2019-05-07 CN disclosed