Mecrylate

Mecrylate

SCHEMBL28286396

C=C(C#N)C(=O)OC.N#CC#N

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
TSHR P16473 1/20 0.61
IDO1 P14902 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MCL1 Q07820 2/20 0.33
CYP2C9 P11712 1/20 0.31
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mecrylate SCHEMBL15701 0.97
Mecrylate SCHEMBL30721295 0.95
Mecrylate SCHEMBL27978822 0.93 ALDH1A1 (0.59) ALDH1A1TSHRIDO1TDP1MCL1
Mecrylate SCHEMBL8083330 0.89 ALDH1A1 (0.55) ALDH1A1TSHRIDO1TDP1MCL1
Mecrylate SCHEMBL28005041 0.85 ALDH1A1 (0.52) ALDH1A1TSHRIDO1CYP2C9
SCHEMBL27579229 0.83 ALDH1A1 (0.48) ALDH1A1TSHRIDO1TDP1
Mecrylate SCHEMBL28122698 0.82 ALDH1A1 (0.48) ALDH1A1TSHRIDO1
Mecrylate SCHEMBL28467819 0.80 ALDH1A1 (0.47) ALDH1A1TSHR
Mecrylate SCHEMBL11180526 0.79 ALDH1A1 (0.55) ALDH1A1TSHRCYP2C9MAPT
Mecrylate SCHEMBL8465653 0.79 ALDH1A1 (0.46) ALDH1A1TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105849955-B Binder composition for lithium ion secondary battery electrode, and lithium ion secondary battery 日本合成化学工业株式会社 2019-04-02 CN disclosed