Mecrylate

Mecrylate

SCHEMBL8083330

C=C(C#N)C(=O)O.C=C(C#N)C(=O)OC

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
TSHR P16473 1/20 0.55
IDO1 P14902 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
MCL1 Q07820 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mecrylate SCHEMBL15701 0.91
Mecrylate SCHEMBL28286396 0.89 ALDH1A1 (0.61) ALDH1A1TSHRIDO1TDP1MCL1
Mecrylate SCHEMBL30721295 0.89
Mecrylate SCHEMBL27978822 0.86 ALDH1A1 (0.59) ALDH1A1TSHRIDO1TDP1MCL1
Mecrylate SCHEMBL28005041 0.83 ALDH1A1 (0.52) ALDH1A1TSHRIDO1
SCHEMBL28225973 0.83 ALDH1A1 (0.41) ALDH1A1TSHRTDP1
SCHEMBL9346940 0.82 ALDH1A1 (0.85) ALDH1A1TSHRTDP1EGLN1
Propane SCHEMBL11541314 0.81 ALDH1A1 (0.52) ALDH1A1TSHRTDP1MCL1
Dimethylamine SCHEMBL8412943 0.81 ALDH1A1 (0.41) ALDH1A1TSHRTDP1MCL1
Ethane SCHEMBL3278228 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0910249-B1 RECTAL PLUG AND METHOD OF INTRODUCING SAME INTO A SLAUGHTERED ANIMAL STARCHTECH INC (US) 2000-10-25 EP disclosed
US-5994464-A ELASTOMER MISCIBLE OR COMPATIBLE WITH THE CYANOACRYLATE MONOMER AND CORE-SHELL POLYMER HAVING A RUBBERY CORE AND A SHELL OF A GLASSY POLYMER, THE CORE-SHELL POLYMER BEING COMPATIBLE BUT NOT MISCIBLE WITH THE CYANOACRYLATE MONOMER. THREE BOND., LTD. (JP) 1999-11-30 US disclosed