SCHEMBL28286935

SCHEMBL28286935

CCCc1cnc(CCC)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MPO P05164 1/20 0.44
TPO P07202 1/20 0.44
TSHR P16473 1/20 0.44
LPO P22079 1/20 0.44
CYP2C19 P33261 1/20 0.44
TAS2R38 P59533 1/20 0.44
HTR1B P28222 2/20 0.41
MTOR P42345 1/20 0.41
HRH1 P35367 2/20 0.41
GLA P06280 1/20 0.40
HRH4 Q9H3N8 1/20 0.39
BRS3 P32247 3/20 0.38
KDM1A O60341 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
KDM5A P29375 1/20 0.37
KDM5B Q9UGL1 1/20 0.37
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
KDM4C Q9H3R0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7484552 0.88 GLA (0.39) MPOTPOTSHRLPOCYP2C19
SCHEMBL20438536 0.88 MPO (0.38) MPOTPOTSHRLPOCYP2C19
SCHEMBL9425091 0.85 BRS3 (0.38) HTR1BMTORHRH1GLABRS3
Hydrochloric Acid SCHEMBL6618258 0.83 GLA (0.35) MPOTPOTSHRLPOCYP2C19
SCHEMBL21690701 0.81 BRS3 (0.40) MPOTPOTSHRLPOCYP2C19
SCHEMBL24445917 0.79
SCHEMBL28063353 0.79 GPR84 (0.49) BRS3
SCHEMBL22361953 0.77
SCHEMBL7768510 0.77
SCHEMBL12685100 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476803-B Amine compositions useful for making polyurethane foams 赢创运营有限公司 2022-04-12 CN disclosed
CN-109476803-A It can be used for manufacturing the amine composition of polyurethane foam 赢创德固赛有限公司 2019-03-15 CN disclosed