Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906685 | 1.00 | ALDH1A1 (0.35) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL9578338 | 0.87 | — | — | |
| SCHEMBL20000718 | 0.84 | ALDH1A1 (0.31) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL28125290 | 0.82 | TSHR (0.32) | CYP3A4TSHRATMTDP1KMT2A | |
| SCHEMBL28075242 | 0.81 | ALDH1A1 (0.33) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL10428722 | 0.80 | KMT2A (0.33) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL28068963 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL27459207 | 0.77 | PTGS1 (0.50) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL105903 | 0.77 | PTGS1 (0.46) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL28130248 | 0.77 | PTGS1 (0.50) | ALDH1A1CYP1A2HPGDCYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461876-A | For exhausting the composition and method of CD137+ cell | MAGENTA THERAPEUTICS INC | 2019-11-15 | — | — | CN | disclosed |
| CN-109661400-A | Compositions and methods for depleting CD117+ cells | 美真达治疗公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-109641051-A | For exhausting the composition and method of cell | 美真达治疗公司 | 2019-04-16 | — | — | CN | disclosed |