Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.50 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | WRN | Q14191 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28130248 | 1.00 | PTGS1 (0.50) | PTGS1PTGS2GSTK1MGLLALDH1A1 | |
| SCHEMBL357100 | 0.82 | MGLL (0.48) | PTGS1PTGS2MGLLALDH1A1BLM | |
| SCHEMBL28068963 | 0.80 | ALDH1A1 (0.38) | PTGS1PTGS2MGLLALDH1A1BLM | |
| SCHEMBL14868157 | 0.79 | MGLL (0.55) | PTGS1PTGS2MGLLALDH1A1BLM | |
| SCHEMBL28847998 | 0.79 | MGLL (0.55) | PTGS1PTGS2MGLLALDH1A1BLM | |
| SCHEMBL28087175 | 0.78 | ALDH1A1 (0.40) | PTGS1PTGS2MGLLALDH1A1BLM | |
| SCHEMBL17924940 | 0.78 | MGLL (0.43) | PTGS1PTGS2MGLLALDH1A1BLM | |
| SCHEMBL19569401 | 0.78 | MGLL (0.46) | PTGS1PTGS2MGLLALDH1A1BLM | |
| SCHEMBL28257990 | 0.78 | PTGS1 (0.43) | PTGS1PTGS2GSTK1ALDH1A1NPSR1 | |
| SCHEMBL27906685 | 0.77 | ALDH1A1 (0.35) | ALDH1A1BLMCYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382534-A | METHODS OF TREATING PRLR POSITIVE BREAST CANCER | 里珍纳龙药品有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-110240654-A | In conjunction with the antibody-drug conjugates of CD73 | 复旦大学 | 2019-09-17 | — | — | CN | claimed |
| CN-110167597-A | Aptamer-drug conjugates and uses thereof | 因特欧力多公司 | 2019-08-23 | — | — | CN | claimed |
| CN-109690315-A | Use of human epididymis protein 4(HE4) for assessing responsiveness to MUC16 positive cancer therapy | 豪夫迈·罗氏有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-106687480-B | anti-c-Met antibody, anti-c-Met antibody-cytotoxic drug conjugate and medical application thereof | 苏州盛迪亚生物医药有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-109142750-A | A kind of kit and detection method measuring histonic antibody IgG | 江苏浩欧博生物医药股份有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-109085343-A | A kind of kit and detection method measuring anti-Jo-1 antibody | 江苏浩欧博生物医药股份有限公司 | 2018-12-25 | — | — | CN | claimed |
| CN-108601832-A | The medical usage of anti-C-met antibodies-cytotoxic drug conjugate | 苏州盛迪亚生物医药有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-106188293-A | Anti-C-met antibodies and anti-C-met antibodies-cytotoxic drug conjugate and medical usage thereof | 江苏恒瑞医药股份有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-105646649-A | RGD-peptide-type cationic lipid compound, preparation method thereof, and application of compound to medicine and gene transportation | 大连民族大学 | 2016-06-08 | — | — | CN | claimed |
| CN-105051057-B | Cellular responsibility, long-acting or targeting compstatin analogs and compositions related and method | 阿佩利斯制药公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-110452242-A | Pyrrolobenzodiazepines Zhuo and its conjugate | MEDIMMUNE LTD | 2019-11-15 | — | — | CN | disclosed |
| CN-110433139-A | Anti-egfr antibodies drug conjugates preparation | ABBVIE DEUTSCHLAND | 2019-11-12 | — | — | CN | disclosed |
| CN-110418851-A | The treatment of cancer and diagnostic method | GENENTECH INC | 2019-11-05 | — | — | CN | disclosed |
| CN-110382535-A | anti-GPR 20 antibodies and anti-GPR 20 antibody-drug conjugates | 第一三共株式会社 | 2019-10-25 | — | — | CN | disclosed |
| CN-103998027-A | Methods of using SCD1 antagonists for cancer therapy | HOFFMANN LA ROCHE | 2014-08-20 | — | — | CN | disclosed |
| CN-102933231-A | Cd20 antibodies and uses thereof | IMMUNOGEN INC | 2013-02-13 | — | — | CN | disclosed |
| CN-1159584-C | Medicine box bof testing anti-hepatitis C virus antibody | ϣ�����˹�ɷ�����˾ | 2004-07-28 | — | — | CN | disclosed |
| CN-1299973-A | HCV-free-blood external preparing method | HILONG CO LTD (US) | 2001-06-20 | — | — | CN | disclosed |
| CN-1285514-A | Medicine box bof testing anti-hepatitis C virus antibody | CHIRON CORP (US) | 2001-02-28 | — | — | CN | disclosed |