Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 6/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28287252 | 0.82 | HCAR2 (0.37) | HCAR2KDM4EBACE1BACE2ALDH1A1 | |
| SCHEMBL28287231 | 0.82 | BACE1 (0.31) | BACE1BACE2 | |
| SCHEMBL990507 | 0.81 | KDM4E (0.42) | HCAR2ASPHKDM4EKDM8BACE1 | |
| SCHEMBL29447044 | 0.81 | KDM4E (0.42) | HCAR2ASPHKDM4EKDM8BACE1 | |
| SCHEMBL630565 | 0.75 | — | — | |
| SCHEMBL28115935 | 0.75 | SIRT6 (0.47) | HCAR2ASPHKDM4EKDM8BACE1 | |
| SCHEMBL19556530 | 0.74 | HCAR2 (0.53) | HCAR2KDM4EALDH1A1 | |
| SCHEMBL15352404 | 0.69 | SIRT6 (0.52) | ASPHKDM4EKDM8BACE1BACE2 | |
| SCHEMBL29447022 | 0.69 | SIRT6 (0.52) | ASPHKDM4EKDM8BACE1BACE2 | |
| 2-Picolinic Acid SCHEMBL28871212 | 0.69 | P4HTM (0.61) | HCAR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641854-A | Integration stress access regulator | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |