Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15972146 | 0.78 | POLB (0.38) | POLBCYP1A2TSHRALDH1A1HDAC3 | |
| SCHEMBL2121840 | 0.75 | CYP1A2 (0.42) | POLBCYP1A2TSHRMAPTAPAF1 | |
| SCHEMBL8320763 | 0.74 | KMT2A (0.47) | CYP1A2TSHRKMT2A | |
| SCHEMBL3136524 | 0.68 | CYP1A2 (0.56) | POLBCYP1A2TSHRMAPTHDAC3 | |
| SCHEMBL12237327 | 0.68 | POLB (0.53) | POLBCYP1A2TSHRMAPTAPAF1 | |
| SCHEMBL18742337 | 0.67 | POLB (0.42) | POLBCYP1A2TSHRMAPTAPAF1 | |
| SCHEMBL28536843 | 0.67 | POLB (0.42) | POLBCYP1A2TSHRMAPTAPAF1 | |
| SCHEMBL19690397 | 0.67 | CYP1A2 (0.59) | POLBCYP1A2TSHRMAPTALDH1A1 | |
| SCHEMBL21225274 | 0.67 | POLB (0.42) | POLBCYP1A2TSHRMAPTAPAF1 | |
| SCHEMBL25583841 | 0.67 | POLB (0.51) | POLBCYP1A2TSHRMAPTAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106242938-B | Fluorene ethylene derivative and synthetic method thereof | 沈阳大学 | 2019-04-23 | — | — | CN | disclosed |