SCHEMBL2121840

SCHEMBL2121840

CC([C]=O)C1c2ccccc2-c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
TSHR P16473 1/20 0.42
KMT2A Q03164 5/20 0.40
MEN1 O00255 4/20 0.40
POLB P06746 3/20 0.40
GPR3 P46089 2/20 0.40
ATM Q13315 1/20 0.40
HTR2A P28223 2/20 0.35
NCOR2 Q9Y618 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
CDC25B P30305 2/20 0.35
ACHE P22303 2/20 0.33
BCHE P06276 2/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26666870 0.77 CYP1A2 (0.44) CYP1A2TSHRKMT2AMEN1POLB
SCHEMBL3094602 0.77 CYP1A2 (0.44) CYP1A2TSHRKMT2AMEN1POLB
SCHEMBL3919889 0.77 GPR3 (0.46) CYP1A2TSHRKMT2AMEN1POLB
SCHEMBL6675583 0.77 GPR3 (0.46) CYP1A2TSHRKMT2AMEN1POLB
SCHEMBL25412588 0.76 POLB (0.38) CYP1A2TSHRKMT2AMEN1POLB
SCHEMBL431543 0.76 POLB (0.38) CYP1A2TSHRKMT2AMEN1POLB
SCHEMBL25436333 0.76 POLB (0.38) CYP1A2TSHRKMT2AMEN1POLB
SCHEMBL28287294 0.75 POLB (0.44) CYP1A2TSHRKMT2AMEN1POLB
Hydrochloric Acid SCHEMBL8676324 0.73 GPR3 (0.43) CYP1A2TSHRKMT2AMEN1POLB
Iodide SCHEMBL8675587 0.73 GPR3 (0.43) CYP1A2TSHRKMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106716195-A Polarizing plate and liquid crystal display device 柯尼卡美能达株式会社 2017-05-24 CN disclosed
US-20140178606-A1 CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-06-26 US disclosed
US-8477275-B2 Optical film and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-20130128359-A1 OPTICAL FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY APPARATUS FUJIFILM CORPORATION (JP) 2013-05-23 US disclosed
WO-2013032016-A1 CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-03-07 WO disclosed
CN-101333305-B Cellulose acylate composition, cellulose acylate film, and its applications FUJI PHOTO FILM CO LTD 2012-10-24 CN disclosed
CN-101392071-B Cellulose acylate film, phase difference film, optical compensation film, polaroid and image display device FUJI PHOTO FILM CO LTD 2012-10-10 CN disclosed
CN-102445730-A Optical film, polarizing plate and liquid crystal display device FUJIFILM CORP 2012-05-09 CN disclosed
US-20120092594-A1 OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-20120092595-A1 Optical film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-20110251393-A1 HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME KYOTO UNIVERSITY (JP) 2011-10-13 US disclosed
EP-2357177-A1 HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME Kyoto University (JP) 2011-08-17 EP disclosed
US-20090082557-A1 CELLULOSE ACYLATE FILM AND ITS APPLICATIONS FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
CN-101392071-A Cellulose acylate film, phase difference film, optical compensation film, polaroid and image display device FUJIFILM CORP (JP) 2009-03-25 CN disclosed
CN-101333305-A Cellulose acylate composition, cellulose acylate film, and its applications FUJIFILM CORP (JP) 2008-12-31 CN disclosed
US-20080241430-A1 CELLULOSE COMPOUND COMPOSITION, CELLULOSE COMPOUND FILM, OPTICALLY COMPENSATORY SHEET, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251393-A1 HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME AADAT, AASDHPPT, AZI2 CYP1A2 229/4885TSHR 2296/4885KMT2A 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.