SCHEMBL28287515

SCHEMBL28287515

CCCNc1ccc(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.58
CSNK1A1 P48729 2/20 0.58
CSNK1D P48730 2/20 0.58
CSNK1G1 Q9HCP0 2/20 0.58
MAOA P21397 2/20 0.58
FGR P09769 1/20 0.58
PIM1 P11309 1/20 0.58
DYRK1A Q13627 1/20 0.58
HIPK2 Q9H2X6 1/20 0.58
MEN1 O00255 7/20 0.54
KMT2A Q03164 7/20 0.54
POLB P06746 6/20 0.54
BLM P54132 4/20 0.54
NSD2 O96028 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
TOP2B Q02880 1/20 0.52
MMP14 P50281 1/20 0.52
RAB9A P51151 2/20 0.50
NPC1 O15118 1/20 0.50
MTOR P42345 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL10780560 0.98 ADORA2A (0.56) ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA
SCHEMBL11645881 0.91 ADORA2A (0.54) ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA
SCHEMBL11131632 0.91 POLB (0.63) MAOAMEN1KMT2APOLBBLM
SCHEMBL29940221 0.91 POLB (0.63) MAOAMEN1KMT2APOLBBLM
SCHEMBL11423638 0.90 ADORA2A (0.53) ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA
SCHEMBL8647027 0.89 ADORA2A (0.51) ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA
SCHEMBL10613217 0.88 ADORA2A (0.61) ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA
SCHEMBL595621 0.85 TOP2B (0.68) ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA
SCHEMBL14582002 0.84 POLB (0.56) MEN1KMT2APOLBBLMNSD2
SCHEMBL3739316 0.83 ADORA2A (0.51) ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109554004-A Pigment dispersing agent and application thereof 江苏丽王科技股份有限公司 2019-04-02 CN claimed
CN-109554004-A Pigment dispersing agent and application thereof 江苏丽王科技股份有限公司 2019-04-02 CN disclosed